Fundings & Exits
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The medical industry is sitting on a huge trove of data, but in many cases it can be a challenge to realize the value of it because that data is unstructured and in disparate places.
Today, a startup called Mendel, which has built an AI platform both to ingest and bring order to that body of information, is announcing $18 million in funding to continue its growth and to build out what it describes as a “clinical data marketplace” for people not just to organize, but also to share and exchange that data for research purposes. It’s also going to be using the funding to hire more talent — technical and support — for its two offices, in San Jose, California and Cairo, Egypt.
The Series A round is being led by DCM, with OliveTree, Zola Global, and MTVLP, and previous backers Launch Capital, SOSV, Bootstrap Labs and chairman of UCSF Health Hub Mark Goldstein also participating.
The funding comes on the heels of what Mendel says is a surge of interest among research and pharmaceutical companies in sourcing better data to gain a better understanding of longer-term patient care and progress, in particular across wider groups of users, not just at a time when it has been more challenging to observe people and run trials, but in light of the understanding that using AI to leverage much bigger data sets can produce better insights.
This can be important, for example, in proactively identifying symptoms of particular ailments or the pathology of a disease, but also recurring and more typical responses to specific treatment courses.
We previously wrote about Mendel back in 2017 when the company had received a seed round of $2 million to better match cancer patients with the various clinical trials that are regularly being run: the idea was that certain trials address specific types of cancers and types of patients, and those who are willing to try newer approaches will be better or worse suited to each of these.
It turned out, however, that Mendel discovered a problem in the data that it would have needed to enable its matching algorithms to work, said Dr. Karim Galil, Mendel’s CEO and founder.
“As we were trying to build the trial business, we discovered a more basic problem that hadn’t been solved,” he said in an interview. “It was the reading and understanding medical records of a patient. If you can’t do that you can’t do trial matching.”
So the startup decided to become an R&D shop for at least three years to solve that problem before doing anything with trials, he continued.
Although there are today many AI companies that are parsing unstructured information in order to extract better insights, Mendel is what you might think of as part of the guard of tech companies that are building out specific AI knowledge bases for distinct verticals or areas of expertise. (Another example from another vertical is Eigen, working in the legal and finance industries, while Google’s DeepMind is another major AI player looking at ways of better harnessing data in the sphere of medicine.)
The issue of “reading” natural language is more nuanced than you might think in the world of medicine. Galil compared it to the phrase “I’m going to leave you” in English, which could just as easily mean someone is departing, say, a room, as someone is walking out of a relationship. The “true” answer — and as we humans know even truth can be elusive — can only start to be found in the context.
The same goes for doctors and their observation notes, Galil said. “There is a lot hidden between the lines, and problems can be specific to a person,” or to a situation.
That has proven to be a lucrative area to tackle.
Mendel uses a mix of computer vision and natural language processing built by teams with extensive experience in both clinical environments and in building AI algorithms and currently provides tools to automate clinical data abstraction, OCR, special tools to redact and remove personal identifiable information automatically to share records, search engines to search clinical data and — yes — an engine to enable better matching of people to clinical trials. Customers include pharmaceutical and life science companies, real-world data and real-world evidence (RWD and RWE) providers and research groups.
And to underscore just how much there is still left to do in the world of medicine, along with this funding round, Mendel is announcing a partnership with eFax, an online faxing solution used by a huge number of healthcare providers.
Faxing is totally antiquated in some parts of the world now — I’m not even sure that people the age of my children (tweens) even know what a “fax” is — but they remain one of the most-used ways to transfer documents and information between people in the worlds of healthcare and medicine, with 90% of the industry using them today. The partnership with Mendel will mean that those eFaxes will now be “read” and digitized and ingested into wider platforms to tap that data in a more useful way.
“There is huge potential for the global healthcare industry to leverage AI,” said Mendel board member and partner at DCM, Kyle Lui, in a statement. “Mendel has created a unique and seamless solution for healthcare organizations to automatically make sense of their clinical data using AI. We look forward to continuing to work with the team on this next stage of growth.”
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Hydrogen-based generators are an environmentally friendly alternative to ones powered by diesel fuel. But many rely on solar, hydro or wind power, which aren’t available all the time. Brisbane-based Endua is making hydrogen-based power generators more accessible by using electrolysis to create more hydrogen and storing it for long-term use. The startup’s technology was developed at CSIRO, Australian’s national science agency, and is being commercialized by Main Sequence, the venture fund founded by CSIRO and Ampol, one of the country’s largest fuel companies.
Main Sequence’s venture science model means that it first identifies a global challenge, then brings together the technology, team and investors to launch a startup that can address that problem. Through the program, Paul Sernia, the founder of electric vehicle charger maker Tritium, was brought on to serve as Endua’s chief executive officer, working with Main Sequence partner Martin Duursma to commercialize the hydrogen-based power generation and storage technology developed at CSIRO. Ampol will serve as Endua’s industry partner.
Endua is backed by $5 million AUD (about $3.9 million USD) from Main Sequence, CSIRO and Ampol. The company plans to launch in Australia first before expanding into other countries.
Sernia told TechCrunch that Endua was created to “solve one of the biggest problems facing the transition to renewable energy — how to store renewable energy in large quantities, for long periods of time.”
Endua’s modular power banks can run up to 150 kilowatts per pack and be extended for different use cases, serving as an alternative to power generators that run on diesel fuel. Batteries serve as backup, but Endua’s goal is to deliver renewable energy that can be stored in large quantities, enabling off-grid infrastructure and communities to have self-sustaining power sources.
“Hydrogen electrolysis technology has been around for quite some time but it still has a long way to go to meet the expectations of commercial markets and be cost-effective when compared to existing energy sources,” Sernia said. “The technology we’ve developed with CSIRO enables us to make the cost more affordable compared to fossil fuel sources, more reliable and easily maintained in remote communities.”
The startup plans to focus on industrial clients before reaching smaller businesses and residences. “One of the biggest opportunities, that few have really tackled, is that of diesel generator users like regional communities, mines or remote infrastructure,” Sernia said. “In farming, Endua’s solution could be used to power equipment such as a bore or irrigation pumps.” The power banks can plug into existing renewable energy systems, including solar and wind, to make the switch economical for users, he added. Water is part of the electrolysis process, but only a small amount is needed.
“Batteries are a great way to deliver dispatchable power in small increments and are a complementary part of the overall transition plan, but we’re focusing on delivering renewable energy that can be stored in large quantities, for large periods of time, so communities and remote infrastructure can access reliable, renewable energy at any time of day,” Sernia told TechCrunch.
Ampol is working with Endua as part of its Future Energy and Decarbonisation Strategy. It will test and commercialize Endua’s tech to reach its 80,000 B2B customers, focusing first on the off-grid diesel generator market, which the company said generates 200,000 tonnes of carbon emissions per year.
In a press statement, Ampol managing director and CEO Matthew Halliday said, “We are excited to be involved with Endua, which is part of our commitment to extending our customer value proposition by finding and developing new energy solutions that will assist with their energy transition.”
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Xometry, a Maryland-based service that connects companies with manufacturers with excess production capacity around the world, filed an S-1 form with the U.S. Securities and Exchange Commission announcing its intent to become a public company.
Growth aside, it’s clear that Xometry is no modern software business, at least from a revenue-quality profile.
As the global supply chain tightened during the pandemic in 2020, a company that helped find excess manufacturing capacity was likely in high demand. CEO and co-founder Randy Altschuler described his company to TechCrunch this way last September upon the announcement of a $75 million Series E investment:
“We’ve created a marketplace using artificial intelligence to power it, and provide an e-commerce experience for buyers of custom manufacturing and for suppliers to deliver that manufacturing,” Altschuler said at the time. Xometry raised nearly $200 million while private, per Crunchbase data.
With Xometry, companies looking to build custom parts now have the ability to do so in a digital way. Rather than working the phones or starting an email chain, they can go into the Xometery marketplace, define parameters for their project and find a qualified manufacturer who can handle the job at the best price.
As of last September, the company had built relationships with 5,000 manufacturers around the world and had 30,000 customers using the platform.
At the time of that funding round, perhaps it wasn’t a coincidence that the company’s lead investor was T. Rowe Price. When an institutional investor is involved in a late-stage round, it’s usually a sign that the company is ready to start thinking about an IPO. Altschuler said it was definitely something the company was considering and had brought on a CFO, too, another sign that a company is ready to take that next step.
So what do Xometry’s financials look like as it heads to the public markets? We took a look at the S-1 to find out.
Xometry makes money in two ways. The first comes from one part of its marketplace, with the company generating “substantially all of [its] revenue” from charging “buyers on its platform.” The other way that Xometry engenders top line is seller-related services, including financial work. The company notes that seller-generated revenues were just 5% of its 2020 total, though it does expect that figure to rise.
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Google has selected 30 startups to receive a share of its $2 million Black Founders Fund in Europe, providing these companies with a spot of cash, some valuable cloud services and a bit of good old-fashioned networking among the Google crew.
The fund was announced last fall as part of a company-wide effort toward “building a more equitable future for everyone,” alongside grants and new sponsorships. More than 800 companies applied and Google interviewed 100 of them, ultimately winnowing that down to the 30 announced today.
Each company will receive “up to” $100,000 in non-dilutive funding, and up to $120,000 in Ads grants and $100,000 in Cloud credits. (I’ve asked Google for more details on how the fund was divided, and if any company received this full amount. I’ll update if I hear back.)
They’ll also get access to Google’s entrepreneurial network, tech support and some other assets that don’t have hard numbers associated with them.
All the startups are led by Black founders, and 40% by women of color. One of the latter is Nancy de Fays, co-founder of LINE, which makes these cool battery-hub combos for the MacBook “Pro” that add a ton of ports and battery life and look sweet to boot. I’ve learned a lot chatting with her at trade shows, and regret that I do most of my work at a desktop so I don’t have an excuse to use one of the company’s gadgets.
In response to being selected for Google funding, de Fays penned a blog post exhorting corporations to throw their weight around in favor of social change, and for startups to lead the way in diversity and equity:
We buy values and standards more than we buy the product itself. We buy ideals of life more than the actual features. Putting the these two parameters in the equation – the capability of big corps to shout loud, and consumers’ receptiveness to brands values and messages – it does make sense to me that to drive such a society change, big companies should voice and convey strong messages.
Founders need to build diverse teams without falling into compassion fatigue. They must show empathy and respect and bring onboard the best talents. Period. They need to be outspoken about their values, convey a strong, global mindset and build their organisation around them. And if they find themselves scoring low on diversity along the way, they should question themselves on the why and act on it without doing charity.
It’s something of a counterpoint to the idea, also commonly expressed these days, that companies should be mission-focused and objective.
Here are the other 29 companies that Google will be giving a boost to (descriptions taken from the blog post):
Feels like we’ll be hearing from most of these folks again. You can find out more about Google’s startup programs here.
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The agriculture sector is ripe for technological improvements, but beyond satellite-based crop management and bees-as-a-service, the actual people who work in the fields should be benefiting as well. Ganaz, empowered by a $7 million A round, aims to change how people with little documentation and no bank account get paid and send money with a modern workforce stack that embraces low tech as well.
Growers — that is to say, the companies that own and operate the fields and sell the crops — are under pressure from multiple directions as wages rise, regulations increase and willing workers dwindle. They need to save money to make money, but they can’t do so by paying less; in addition to being cruel to a marginalized class of people, it would only exacerbate the labor shortage in the sector.
There are plenty of companies out there that help save costs by automating things like payroll and onboarding, but the agriculture business has some unique limitations.
“It’s still operating like it’s the ’80s,” explained Ganaz founder and CEO Hannah Freeman. The number one service these workers rely on is check cashing or payday loans, and fees from these, currency exchange, ATM fees and remittances eat up a significant portion of each paycheck. “The workforce in our world definitely doesn’t have corporate email and rarely uses personal email. They have trouble downloading and using mobile apps, don’t use usernames. But they’re very conversant in WhatsApp and SMS — so you have to kind of know how to build for them.”
The ecosystem has parallels to other regions that have stuck with older, cheaper technologies instead of adopting the latest and most expensive tech. Entire markets in Africa and South America, for instance, run on text-based commerce taking place on aging and unreliable infrastructure.
Ganaz has opted for a hybrid approach. The company’s platform offers several services on both the worker and employer side.
Onboarding and basic training can be done simply and intuitively for people who may not be highly literate, via tablets loaded with apps that also operate offline. The most common alternative seems to be file folders served out of a crate in the back of a pickup — that’s not a dig, it’s just what has made sense for years for this highly fluid, distributed workforce.
Payment and balance checks all happen over SMS or WhatsApp with workers, but for sensitive information they are shunted to a web app; similarly, integrated remittance partnerships are coming that will keep things simple and reduce fees.
On the employer side, the workers and all their vital stats and documents are tracked centrally in the kind of interface companies have grown to expect. And Ganaz works as an intermediary to send text alerts and questions.
So far Ganaz has 75 employers signed up, one of which is a Costco supplier group, and all told around 175,000 workers on the platform. Their ARR and user count both approximately tripled year over year, so they’re clearly on to something.
The company has tempered its rapid growth with designation as a public benefit corporation, which emphasizes the intention to do more than grow shareholder value. I asked about the tension between needing to show a profit and working in the service of a marginalized group.
“This keeps me up at night,” admitted Freeman. “We try to make sure to set ourselves up to be true to our mission. That means the folks we hire, our board of directors… we want to make sure we’re empathizing and honoring the trust we’ve built with people.”
That includes investors as well, and Freeman noted that the company ended up going with Trilogy as lead for this round partly because of that firm’s experience with Remit.ly.
For instance, Freeman noted, while it would be easy to juice profits by bumping ATM fees, that directly harms the people they’re trying to help. Instead, when they issue their payroll Mastercard later this year, that will allow workers to skip the check cashing step and its fees, and then Ganaz gets a share of the normal card transaction fee. “We can be equally successful that way,” said Freeman, and it doesn’t just replace another predatory structure.
After the cards the plan is to automate remittances, so a user can easily choose to send money to their family in a way that minimizes handling fees and so on. And there will be other options, accessible via text, to choose where money goes if not to the card.
Ganaz’s main market is the U.S. and Mexico, since the agriculture business and workforce are both largely binational, but there are other targets on the horizon. First, though, the company wants to solidify its position and feature set here. “There’s no breakaway winner yet, so we want to be that winner,” said Freeman.
The $7 million round also had participation from Bessemer Venture Partners, Founders’ Co-op, Taylor Ventures, AgFunder and Techstars. Rapid expansion and aggressive pursuit of the roadmap are next up for Ganaz.
“We are conscious of both the huge opportunity ahead of us to digitize billions of dollars in payroll, as well as the responsibility to build inclusive, low-cost, wealth-building tools for workers,” said Freeman.
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What happens to technology companies with slowing growth and a rising focus on profitability before they reach behemoth scale? How much does the market value hypergrowth?
Just because a technology startup has a hot start, that doesn’t mean it will grow quickly forever. Most will wind up somewhere in the middle — or worse. Put simply, there is a larger number of tech companies that do fine or a little bit worse after they reach scale.
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But what every investor hopes for is the hot company that can keep growth alive even after reaching material scale, running through walls, competitors, economic headwinds and anything else that comes its way. Those companies don’t end up worth a few hundred million, or a billion, but can end up valued in the dozens of billions or more.
In reverse, tech companies — even those with strong gross margins — with slipping growth can see their multiples compress rapidly. Then, the vultures circle.
Which explains some of the news we’ve seen recently in the market. As Dropbox comes under fresh pressure from external parties, joining its erstwhile rival Box in the public-market growth penalty box, we’re seeing companies like Braze, Gong, Shippo and others rip ahead with rapid-fire funding rounds or public brags about their growth.
While the differential between the two groups is clear, it’s still worth exploring in more detail. Let’s talk about the growth dividend. Or, if you’d prefer, the existential cost of growth deceleration.
The news this week that Dropbox has attracted an activist shareholder should not have been a surprise. Its former rival Box is in the midst of a long-running struggle with an activist investor of its own. (More here.)
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Climate change is intensifying across the globe, and one of the most challenging cases is Japan. In addition to lying on a major fault, the archipelago is increasingly inundated from rising sea levels that make the country more prone to disasters. A decade ago, the Tohoku earthquake and tsunami dealt billions of dollars in damage, and the recovery from that tragedy remains a major international relations flashpoint.
Technology to address disasters and resilience is a key area of venture capital investment these days, and now another startup in the space is proving that there is widespread interest in this growing market.
One Concern, which builds a platform to model and simulate community resilience and response to earthquakes, floods and other natural disasters, announced this morning that it has raised $45 million from SOMPO Holdings, the holding company of Japan’s SOMPO, one of the country’s largest insurers. The investment is part of a total $100 million, multi-year deal that will plug One Concern’s platform into the Japanese market.
Japan has been something of a gem in One Concern’s market development the past few years. The startup hired Hitoshi Akimoto as country manager for Japan in late 2019 before formally announcing that it was expanding to Japan in February 2020. In August last year, it announced a strategic partnership with SOMPO, and the insurer’s holding company invested $15 million. Today’s deal expands that partnership further.
According to its press release, One Concern will sell its platform to six or more Japanese cities as part of the tie-up.
Previously, One Concern had raised three rounds of capital according to Crunchbase and SEC filings: a seed round in October 2015, a $33 million Series A round led by NEA in 2017 and a $37 million round also co-led by NEA. The company was founded in 2015.
Update June 3, 2021: Rephrased SOMPO Holdings as the parent company of SOMPO, and not its venture wing.
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Meet Lightyear, a new London-based startup coming out of stealth today. The company is building a stock trading app with a focus on creating a truly commission-free app. In addition to waving account fees and trading fees, Lightyear doesn’t charge foreign exchange fees either — up to a certain point.
The two founders met when they were working at Wise — then known as TransferWise. That’s why it makes sense that Lightyear wants to stand out from the crowd with lower foreign exchange fees.
Martin Sokk, co-founder and CEO of Lightyear, worked at Wise between 2012 and 2017. He held various roles, such as head of product, head of people and head of operations. Mihkel Aamer, Lightyear’s other co-founder and CTO, was an engineering lead at Wise between 2013 and 2019.
“Having spent my career in financial services, I’ve seen the good, the bad and the ugly. I believe retail investing in Europe is still very much ‘the ugly’ — we’re talking about sneaky fees, less access and complicated products remaining as the status quo,” Aamer said in a statement. “We’re building something that will change that by opening up investing to everyone, whichever global market they want to invest in and however much they want to invest.”
As a user, you can expect a mobile app that lets you buy and sell shares and ETFs. There will be 1,500 stocks and ETFs from multiple markets at launch. Customers won’t pay any account fees, trading fees and foreign exchange fees. But there will be a limit on foreign exchange fees. After £3,000 per month, users will pay 0.35% in FX fees.
The app isn’t quite ready just yet, as Lightyear is opening up a waitlist today. The product should roll out at some point during the third quarter of this year.
Image Credits: Lightyear
Lightyear has raised a $1.5 million pre-seed funding round co-led by the new unnamed fund formed by Wise co-founder Taavet Hinrikus and Teleport co-founder Sten Tamkivi. This is their first investment through this new venture. Skype co-founder Jaan Tallinn is also co-leading the fund through Metaplanet. There are also several business angels participating in today’s funding round, including Checkout.com CTO Ott Kaukver, former president of Robinhood U.K. Wander Rutgers and Veriff founder Kaarel Kotkas.
It’s a nice list of investors, but the company will face tough competition from other startups — you’ll likely end up paying more fees if you use one of these competitors, but they’re already well established. For instance, Berlin-based stock trading app Trade Republic has recently raised $900 million. In the U.K., Freetrade has also managed to attract 600,000 users.
And yet, more importantly, Lightyear also competes with legacy brokers. Unlike in the U.S., the vast majority of retail investors still rely on traditional banks and web platforms for stock trading. There will be room for more than one company in this space. So let’s see how Lightyear executes in the coming months.
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With wildfires becoming an ever more devastating annual phenomenon, it is in the whole planet’s interest to spot them and respond as early as possible — and the best vantage point for that is space. OroraTech is a German startup building a constellation of small satellites to power a global wildfire warning system, and will be using a freshly raised €5.8 million (~$7 million) A round to kick things off.
Wildfires destroy tens of millions of acres of forest every year, causing immense harm to people and the planet in countless ways. Once they’ve grown to a certain size, they’re near impossible to stop, so the earlier they can be located and worked against, the better.
But these fires can start just about anywhere in a dried out forest hundreds of miles wide, and literally every minute and hour counts — watch towers, helicopter flights and other frequently used methods may not be fast or exact enough to effectively counteract this increasingly serious threat. Not to mention they’re expensive and often dangerous jobs for those who perform them.
OroraTech’s plan is to use a constellation of about 100 satellites equipped with custom infrared cameras to watch the entire globe (or at least the parts most likely to burst into flame) at once, reporting any fire bigger than 10 meters across within half an hour.
To start out with, the Bavarian company has used data from over a dozen satellites already in space, in order to prove out the service on the ground. But with this funding round they are set to put their own bird in the air, a shoebox-sized satellite with a custom infrared sensor that will be launched by Spire later this year. Onboard machine learning processing of this imagery simplifies the downstream process.
Fourteen more satellites are planned for launch by 2023, presumably once they’ve kicked the proverbial tires on the first one and come up with the inevitable improvements.
“In order to cover even more regions in the future and to be able to give warning earlier, we aim to launch our own specialized satellite constellation into orbit,” said CEO and co-founder Thomas Grübler in a press release. “We are therefore delighted to have renowned investors on board to support us with capital and technological know-how in implementing our plans.”
Those renowned investors consist of Findus Venture and Ananda Impact Ventures, which led the round, followed by APEX Ventures, BayernKapital, Clemens Kaiser, SpaceTec Capital and Ingo Baumann. The company was spun out of research done by the founders at TUM, which maintains an interest.
“It is absolutely remarkable what they have built up and achieved so far despite limited financial resources and we feel very proud that we are allowed to be part of this inspiring and ambitious NewSpace project,” APEX’s Wolfgang Neubert said, and indeed it’s impressive to have a leading space-based data service with little cash (it raised an undisclosed seed about a year ago) and no satellites.
It’s not the only company doing infrared imagery of the Earth’s surface; SatelliteVu recently raised money to launch its own, much smaller constellation, though it’s focused on monitoring cities and other high-interest areas, not the vast expanse of forests. And ConstellR is aimed (literally) at the farming world, monitoring fields for precision crop management.
With money in its pocket Orora can expand and start providing its improved detection services, though sadly, it likely won’t be upgrading before wildfire season hits the northern hemisphere this year.
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Confluent became the latest company to announce its intent to take the IPO route, officially filing its S-1 paperwork with the U.S. Securities and Exchange Commission this week. The company, which has raised over $455 million since it launched in 2014, was most recently valued at just over $4.5 billion when it raised $250 million last April.
What we can see in Confluent is nearly an old-school, high-burn SaaS business. It has taken on oodles of capital and used it in an increasingly expensive sales model.
What does Confluent do? It built a streaming data platform on top of the open-source Apache Kafka project. In addition to its open-source roots, Confluent has a free tier of its commercial cloud offering to complement its paid products, helping generate top-of-funnel inflows that it converts to sales.
Kafka itself emerged from a LinkedIn internal project in 2011. As we wrote at the time of Confluent’s $50 million Series C in 2017, the open-source project was designed to move massive amounts of data at the professional social network:
At its core, Kafka is simply a messaging system, created originally at LinkedIn, that’s been designed from the ground up to move massive amounts of data smoothly around the enterprise from application to application, system to system or on-prem to cloud — and deal with extremely high message volume.
Confluent CEO and co-founder Jay Kreps wrote at the time of the funding that events streaming is at the core of every business, reaching sales and other core business activities that occur in real time that go beyond storing data in a database after the fact.
“[D]atabases have long helped to store the current state of the world, but we think this is only half of the story. What is missing are the continually flowing stream of events that represents everything happening in a company, and that can act as the lifeblood of its operation,” he wrote.
That’s where Confluent comes in.
But enough about the technology. Is Confluent’s work with Kafka a good business? Let’s find out.
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